Fluoride protects boronic acids in the copper(I)-mediated click reaction.
نویسندگان
چکیده
Fluoride has been found to protect boronic acids from copper(i)-mediated decomposition; such findings should be very useful for the preparation of boronic acid-based carbohydrate sensors and boronic acid conjugates using the copper(i)-mediated click reaction.
منابع مشابه
Click reactions and boronic acids: applications, issues, and potential solutions.
Boronic acids have been widely used in a wide range of organic reactions, in the preparation of sensors for carbohydrates, and as potential pharmaceutical agents. With the growing importance of click reactions, inevitably they are also applied to the synthesis of compounds containing the boronic acid moiety. However, such applications have unique problems. Chief among them is the issue of coppe...
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ورودعنوان ژورنال:
- Chemical communications
دوره 35 شماره
صفحات -
تاریخ انتشار 2009